1376933-35-5Relevant academic research and scientific papers
Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles
Cai, Yunfei,Li, Jun,Chen, Weiliang,Xie, Mingsheng,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
, p. 2726 - 2729 (2012)
Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles has been developed via cooperative catalysis of a chiral N,N′-dioxide- Sc(OTf)3 complex and a Bronsted base. Utilizing readily available N-(phenylthio)phthalimide as the sulfur source, a wide range of optically active 3-phenylthiooxindoles were obtained in excellent yields with excellent enantioselectivities under mild reaction conditions.
