137697-98-4

Basic information

• Product Name: Benzoic acid, 3,5-bis[(aminothioxomethyl)amino]-, ethyl ester
• CAS NO: 137697-98-4
• Molecular Formula: C11H14N4O2S2
• Molecular Weight: 298.39
• Mol File: 137697-98-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3,5-bis[(aminothioxomethyl)amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3,5-bis[(aminothioxomethyl)amino]-, ethyl ester(137697-98-4)
• EPA Substance Registry System: Benzoic acid, 3,5-bis[(aminothioxomethyl)amino]-, ethyl ester(137697-98-4)

Safety Data

• Hazardous Substances Data: 137697-98-4(Hazardous Substances Data)

Upstream product

• 1949-51-5 3,5-diaminobenzoic acid ethyl ester 
• 1147550-11-5 ammonium thiocyanate 

Relevant articles and documents

Bis Basic Substituted Diaminobenzobisthiazoles as Potential Antiarthritic Agents

A series of benzobisthiazoles were screened for antiinflammatory activity in the carrageenan paw edema and adjuvant arthritis tests.Compound 26, 2,6-bis(N,N-diethylamino)benzobisthiazole, was found to inhibit the swelling of the uninjected paw in the prophylactic adjuvant arthritis model with an ED50 of 2.3 mg/kg orally.As with most compounds of this series, 26 was inactive in acute model of inflammation, such as paw edema: like steroids, it showed activity in the granuloma pouch assay but did not inhibit cyclooxygenase, indicating a mode of action different from the classical nonsteroidal antiinflammatory drugs (NSAID's).At doses higher than those producing antiinflammatory activity, 26 had some immunoregulating properties.