1377321-09-9Relevant academic research and scientific papers
Synthesis of β-Thiol Phenylalanine for Applications in One-Pot Ligation-Desulfurization Chemistry
Malins, Lara R.,Giltrap, Andrew M.,Dowman, Luke J.,Payne, Richard J.
, p. 2070 - 2073 (2015)
(Chemical Equation Presented) The efficient synthesis of a β-thiol phenylalanine derivative is described starting from Garner's aldehyde. The utility of this amino acid in peptide ligation-desulfurization chemistry is described, including the trifluoroethanethiol (TFET)-promoted one-pot assembly of the 62 residue peptide hormone augurin.
