1377322-25-2Relevant academic research and scientific papers
N -heterocyclic carbene (NHC)-catalyzed highly diastereo- and enantioselective oxo-Diels-Alder reactions for synthesis of fused pyrano[2,3- b ]indoles
Yang, Limin,Wang, Fei,Chua, Pei Juan,Lv, Yunbo,Zhong, Liang-Jun,Zhong, Guofu
supporting information; experimental part, p. 2894 - 2897 (2012/07/14)
A chiral N-heterocyclic carbene (NHC)-catalyzed Diels-Alder reaction of 2-oxoindolin-3-ylidenes and α-chloroaldehydes was developed for the synthesis of fused pyrano[2,3-b]indoles in good to excellent yields (up to 99%) with high cis-diastereoselectivities (>99:1 dr) and enantioselectivities (up to >99% ee).
