1377337-44-4Relevant academic research and scientific papers
Automated solid-phase synthesis of β-mannuronic acid alginates
Walvoort, Marthe T. C.,Van Den Elst, Hans,Plante, Obadiah J.,Kroeck, Lenz,Seeberger, Peter H.,Overkleeft, Herman S.,Van Der Marel, Gijsbert A.,Codee, Jeroen D. C.
, p. 4393 - 4396 (2012)
A big step towards routine: The title synthesis provides mannuronic acid alginate fragments featuring up to 12 cis-mannosidic linkages, in multi-milligram quantities (see scheme; Bn=benzyl, Lev=levulinoyl). Mannuronic acid building blocks were used in a second-generation carbohydrate synthesizer to secure the stereoselective introduction of the β-mannosidic bonds in a fully automated fashion. Copyright
