137743-24-9Relevant articles and documents
Multivariate analysis by the minimum spanning tree method of the structural determinants of diphenylethylenes and triphenylacrylonitriles implicated in estrogen receptor binding, protein kinase C activity, and MCF7 cell proliferation
Dore,Gilbert,Bignon,De Paulet,Ojasoo,Pons,Raynaud,Miquel
, p. 573 - 583 (2007/10/02)
The response profiles of 36 para-substituted diphenylethylenes (DPEs) and triphenylacrylonitriles (TPEs) have been compared by multivariate analysis. The responses measured were (a) relative binding affinity (RBA) for the cytosol estrogen receptor (ER), (