137756-89-9

Basic information

• Product Name: 4-(2-Hydroxyethyl)phenylboronicacid
• Synonyms: Boronic acid, B-[4-(2-hydroxyethyl)phenyl]-
• CAS NO: 137756-89-9
• Molecular Formula: C₈H₁₁BO₃
• Molecular Weight: 165.9821
• Mol File: 137756-89-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 359.891 °C at 760 mmHg
• Flash Point: 171.456 °C
• Appearance: /
• Density: 1.209 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: 4-(2-Hydroxyethyl)phenylboronicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Hydroxyethyl)phenylboronicacid(137756-89-9)
• EPA Substance Registry System: 4-(2-Hydroxyethyl)phenylboronicacid(137756-89-9)

Safety Data

• Hazardous Substances Data: 137756-89-9(Hazardous Substances Data)

Usage

General Description

4-(2-Hydroxyethyl)phenylboronic acid is a chemical compound that belongs to the group of boronic acids, which are commonly used in organic chemistry due to their ability to form stable covalent bonds with different substances. This particular compound is often used in molecular and synthetic organic chemistry as it interacts readily with a range of other molecules, making it a useful reagent in the synthesis of more complex chemical structures. Additionally, it carries mild acidic properties because of the presence of boron atom. Because the boronic acid functionalities are versatile intermediates, they are often used in research and industrial settings. They also have potential utility in the development of therapeutic agents.

InChI:InChI=1/C8H11BO3/c10-6-5-7-1-3-8(4-2-7)9(11)12/h1-4,10-12H,5-6H2

Upstream product

• 5419-55-6 Triisopropyl borate 
• 4654-39-1 4-bromophenethanol 
• 7732-18-5 water 

Downstream Products

• 415913-36-9 4-{2-[({[(4-Methylphenyl)sulfonyl]amino]carbonyl)oxy]ethyl}phenylboronic acid 
• 202189-78-4 Bilastine 
• 552301-45-8 2-methyl-2-[4'-(2''-hydroxyethyl)phenyl]propanoic acid 
• 137756-90-2 4‐(2‐bromoethyl)phenylboronic acid 

Relevant articles and documents

Tumor diagnosis and treatment integrated boron carrying agent as well as preparation method and application thereof

The invention relates to a tumor diagnosis and treatment integrated boron carrying agent as well as a preparation method and application thereof. A compound of a formula I is provided, the R group is hydrogen or alkyl. Boron atoms attached to a benzene ring may be 10B or natural boron, and at least one fluorine atom in -BF3- is radiolabelled. The present invention relates generally to the field of radiopharmaceuticals and nuclear medicine. The compound provided by the invention can be used for a diagnosis and treatment integrated medicine for tumor diagnosis and BNCT treatment, and a reliable in-vivo distribution result of the medicine is provided through the same chemical structure of the compound.

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.

Imidazole compounds as anti-inflammatory and analgesic agents

This invention provides a compound of the formula (I): wherein: R1 represents a hydrogen atom, an alkyl group, etc.; R2 represents a hydrogen atom, a halogen atom, etc.; R3 represents a hydrogen atom, an alkyl group, etc.;