137769-86-9Relevant academic research and scientific papers
Rhodium(I)-Sulfonated-bdpp Catalysed Asymmetric Hydrogenation of Imines in Aqueous-Organic Two-phase Solvent Systems
Bakos, Jozsef,Orosz, Arpad,Heil, Balint,Laghmari, Mohamed,Lhoste, Paul,Sinou, Denis
, p. 1684 - 1685 (2007/10/02)
The imines ArC(Me)=NCH2Ph (Ar = Ph, 2-MeO-C6H4, 3-MeO-C6H4, 4-MeO-C6H4) are hydrogenated to the corresponding amines with extremely high enantioselectivities up to 96percent under very mild conditions, using rhodium complexes associated with sulfonated bdpp.
Rhodium(I)-catalysed Asymmetric Hydrogenation of Imines
Kang, Guo-Jun,Cullen, William R.,Fryzuk, Michael D.,James, Brian R.,Kutney, James P.
, p. 1466 - 1467 (2007/10/02)
The imines ArC(Me)=NCH2Ph (Ar = Ph, 2-MeO-C6H4, 4-MeO-C6H4) are hydrogenated to the corresponding secondary amines at 1000 psig H2, in 1:1 C6H6/MeOH, using an in situ RhI/(R)-cycphos system (cycphos = Ph2PCH(C6H11)CH2PPh2); a maximum of 91percent enantiomeric excess (e.e.) is achieved at lower temperatures (-25 deg C) in the presence of iodide cocatalyst.
