137777-06-1Relevant academic research and scientific papers
Rearrangements of Pyrrole and Indole Substituted Enol Esters of Cyclohexane-1,3-dione
Oliver, James E.,Lusby, William R.,Waters, Rolland M.
, p. 1565 - 1568 (2007/10/02)
Enol esters 3a and 3b, from cyclohexane-1,3-dione and pyrrole-2-carbonyl chloride and indole-2-carbonyl chloride, respectively, rearranged in the presence of triethylamine to the enamino acids 7 and 12.In the presence of cyanide, 3b, also underwent the expected rearrangement to 4b, whereas only 7 was formed from 3a.Treatment of 7 with mercuric acetate in hot acetic acid resulted in decarboxylation and aromatization to phenol 9.
