1377807-15-2Relevant academic research and scientific papers
Trienamine catalysis with 2,4-dienones: Development and application in asymmetric Diels-Alder reactions
Xiong, Xiao-Feng,Zhou, Quan,Gu, Jing,Dong, Lin,Liu, Tian-Yu,Chen, Ying-Chun
, p. 4401 - 4404 (2012/06/18)
A tri-ing reaction: An asymmetric Diels-Alder cycloaddition of δ,δ-disubstituted 2,4-dienones is possible through the trienamine catalysis of cinchona-based primary amines (see scheme). An array of electron-deficient dienophiles, such as N-substituted maleimides and 3-alkenyl oxindoles, were tolerated, and multifunctional cyclohexene derivatives were obtained in excellent stereoselectivity and with high diastereomer ratios. Copyright
