1377948-99-6Relevant articles and documents
Total synthesis of thelephantin O, vialinin A/Terrestrin A, and terrestrins B-D
Fujiwara, Kenshu,Sato, Takuto,Sano, Yusuke,Norikura, Toshio,Katoono, Ryo,Suzuki, Takanori,Matsue, Hajime
, p. 5161 - 5166 (2012/07/28)
The first total synthesis of natural, unsymmetrical 2′,3′- diacyloxy-p-terphenyls, thelephantin O (1) and terrestrins C and D (2 and 3, respectively), was achieved via a practical route which was also applicable to the synthesis of the symmetrical diesters vialinin A/terrestrin A (4) and terrestrin B (5). Compounds 1-5 exhibited cytotoxicity against cancer cells (HepG2 and Caco2) with IC50 values of 13.6-26.7 μmol/L.