137819-40-0

Upstream product

• 14661-69-9 p-toluenesulfonylhydrazone glyoxylic acid chloride 
• 137819-39-7 (3R,4R)-3-Hydroxymethyl-3-methyl-bicyclohexyl-1,1',3'-trien-4-ol 
• 137819-37-5 Trifluoro-methanesulfonic acid (4aR,8aR)-2,2,4a-trimethyl-4a,7,8,8a-tetrahydro-4H-benzo[1,3]dioxin-6-yl ester 
• 137819-34-2 7-(tert-Butyl-dimethyl-silanyloxymethyl)-1,4-dioxa-spiro[4.5]dec-6-en-8-one 
• 137819-38-6 (4aR,8aR)-6-Cyclohexa-1,3-dienyl-2,2,4a-trimethyl-4a,7,8,8a-tetrahydro-4H-benzo[1,3]dioxine 
• 137819-35-3 (R)-7-(tert-Butyl-dimethyl-silanyloxymethyl)-1,4-dioxa-spiro[4.5]dec-6-en-8-ol 
• 137819-36-4 (R)-2,2-Dimethyl-8,8a-dihydro-4H,7H-benzo[1,3]dioxin-6-one 
• 63028-11-5 cyclohexa-1,3-dien-1-yl trifluoromethanesulfonate 

Relevant academic research and scientific papers

A route for the enantioselective total synthesis of antheridic acid, the antheridium-inducing factor from anemia phyllitidis

An effective route for the total synthesis of antheridic acid (1) has been devised in which the initial chiral intermediate 7 is generated by enantioselective catalytic reduction and transformed in a stereocontrolled fashion into key intermediates 9, 10, 13, and 2.