1378388-19-2

Basic information

• Product Name: 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone
• Synonyms: 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone;7-((2-Bromo-5-chlorobenzyl)oxy)-3,4-dihydronaphthalen-1(2H)-one;CL122
• CAS NO: 1378388-19-2
• Molecular Formula: C₁₇H₁₄BrClO₂
• Molecular Weight: 365.64886
• Mol File: 1378388-19-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 489.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.488±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone(1378388-19-2)
• EPA Substance Registry System: 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone(1378388-19-2)

Safety Data

• Hazardous Substances Data: 1378388-19-2(Hazardous Substances Data)

Usage

General Description

The chemical 7-[(2-Bromo-5-chlorophenyl)methoxy]-3,4-dihydro-1(2H)-naphthalenone, also known as BNTX, is a synthetic compound that belongs to the class of 1(2H)-naphthalenones. It contains a 2-bromo-5-chlorophenyl group and a methoxy group attached to the naphthalenone core. BNTX is a potent and selective κ-opioid receptor antagonist, with potential applications in the study and treatment of pain and addiction. It has shown promising results in preclinical studies for its ability to block the effects of opioid drugs, without affecting the analgesic effects of non-opioid pain medications. Additionally, BNTX may have potential in the treatment of depression and anxiety disorders due to its modulation of the κ-opioid receptor system.

Upstream product

• 66192-24-3 2-bromo-5-chlorobenzyl bromide 
• 22009-38-7 7-hydroxy-1-tetralone 

Downstream Products

• 1378390-29-4 3-(2-bromoacetyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one 
• 1378390-35-2 (2S,5S)-2-(2-(9-bromo-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 1-tert-butyl 5-methylpyrrolidine-1,2-dicarboxylate 
• 1378390-69-2 (2S,4S)-2-(2-(9-bromo-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 1-tert-butyl 4-methylpyrrolidine-1,2-dicarboxylate 
• 1378391-42-4 (2S,4S)-2-(2-(9-bromo-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 1-tert-butyl 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate 
• 1378391-43-5 (2R,4R)-1-tert-butyl 2-(2-(9-((2S,5S)-1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)-5-methylpyrrolidine-2-carbonyloxy)-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate 
• 1378388-20-5 3-chloro-10,11-dihydro-5H-benzo[d]naphtho[2,3-b]pyran-8(9H)-one 
• 1378391-38-8 3-(2-bromo-1-hydroxyethyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one 

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