1378391-86-6

Basic information

• Product Name: (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
• Synonyms: (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 1378391-86-6
• Molecular Formula: C14H22IN3O3
• Molecular Weight: 407.24725
• Mol File: 1378391-86-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 509.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.515±0.06 g/cm3(Predicted)
• PKA: 11.70±0.10(Predicted)
• CAS DataBase Reference: (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester(1378391-86-6)
• EPA Substance Registry System: (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester(1378391-86-6)

Safety Data

• Hazardous Substances Data: 1378391-86-6(Hazardous Substances Data)

Usage

General Description

The chemical (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester is a compound with a complex structure consisting of an imidazole ring, a pyrrolidine ring, and a carboxylic acid group. The ester group suggests that it is likely a derivative of a carboxylic acid. The presence of the iodide and methoxymethyl groups indicates that it may have pharmaceutical or biological activity, as these groups can influence the compound's reactivity and interactions with biological targets. The specific stereochemistry of the compound, with the (2S,4S) configuration, will also impact its biological activity and potential pharmacological properties. This chemical may have potential applications in medicinal chemistry or drug development due to its unique structure and potential biological activity.

Upstream product

• 1378388-16-9 (2S,4S)-N-(tert-butyloxycarbonyl)-4-(methoxymethyl)-pyrrolidine-2-carboxylic acid 
• 1378388-37-4 (2S,4S)-N-(tert-butyloxycarbonyl)-4-(methoxymethyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 1194059-42-1 (2S,4S)-N-(tert-butyloxycarbonyl)-4-(hydroxymethyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 1378388-35-2 (3S,5S)-N-(tert-butoxycarbonyl)-5-(methoxycarbonyl)-pyrrolidine-3-carboxylic acid 
• 1378388-30-7 (2S,4S)-N-(tert-butyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1377049-84-7 methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1-{(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-2-yl)-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate 
• 1844064-96-5 (2S,4S)-2-[5-(2-{(2S,4S)-1-{N-(methoxycarbonyl)-L-valyl}-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromene[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine 
• 1378391-45-7 tert-butyl (2S,4S)-2-[5-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate 
• 1377050-92-4 methyl {(1R)-2-[(2S,4S)-2-(5-{2-[(1S,3S,5S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[3.1.0]hex-3-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl}-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate 

Relevant articles and documents

Compound used for inhibiting hepatitis C virus, and pharmaceutical applications thereof

The invention relates to a compound which is represented by formula I, is used for inhibiting hepatitis C virus, and possesses excellent bioavailability, and a nontoxic pharmaceutically acceptable salt thereof. The compound possesses extremely high inhibition effect on HCV of all genotypes. In the formula I, R is used for representing hydrogen atom, glycyl, L-alanyl, L-leucyl, L-valyl, or L-isoleucyl.