1378426-72-2Relevant academic research and scientific papers
Silver(I)-Promoted conversion of thioamides to amidines: Divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands
Okano, Akinori,James, Robert C.,Pierce, Joshua G.,Xie, Jian,Boger, Dale L.
supporting information; experimental part, p. 8790 - 8793 (2012/07/02)
Development of a general Ag(I)-promoted reaction for the conversion of thioamides to amidines is disclosed. This reaction was employed to prepare a key series of vancomycin aglycon residue 4 substituted amidines that were used to clarify their interaction with model ligands of peptidoglycan precursors and explore their resulting impact on antimicrobial properties.
