1378427-97-4 Usage
Uses
Used in Medicinal Chemistry:
(1R,2S,3R,4R)-1-methoxy-3-(trifluoromethyl)bicyclo[2.2.2]oct-5-en-2-yl-2-[(S)-p-tolylsulfinyl]phenylmethanone is used as a building block or intermediate in the synthesis of pharmaceutical compounds. Its unique structure and functional groups can be utilized to create new drugs with specific therapeutic properties.
Used in Materials Science:
In the field of materials science, (1R,2S,3R,4R)-1-methoxy-3-(trifluoromethyl)bicyclo[2.2.2]oct-5-en-2-yl-2-[(S)-p-tolylsulfinyl]phenylmethanone can be used as a component in the development of advanced materials with tailored properties. Its incorporation into polymers or other materials can lead to new applications in areas such as electronics, coatings, or adhesives.
Used in Chemical Research:
(1R,2S,3R,4R)-1-methoxy-3-(trifluoromethyl)bicyclo[2.2.2]oct-5-en-2-yl-2-[(S)-p-tolylsulfinyl]phenylmethanone serves as a valuable compound for research purposes. Its synthesis and reactivity can be studied to gain insights into the behavior of complex organic molecules and to develop new synthetic methods or strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 1378427-97-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,8,4,2 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1378427-97:
(9*1)+(8*3)+(7*7)+(6*8)+(5*4)+(4*2)+(3*7)+(2*9)+(1*7)=204
204 % 10 = 4
So 1378427-97-4 is a valid CAS Registry Number.
1378427-97-4Relevant academic research and scientific papers
Remote stereocontrol by the sulfinyl group. Diels-Alder reaction of cyclopentadiene with substituted (S)-[2-(p-tolylsulfinyl)styrenes and (S)-[2-(p-tolylsulfinyl)phenyl] vinyl ketones
Maestro, M. Carmen,Fernández-Salas, José Antonio,García Ruano, José L.,Ramírez-Rodríguez, Oney O.,Araya-Maturana, Ramiro
experimental part, p. 4129 - 4137 (2012/07/30)
The ability of a homochiral sulfinyl group at the dienophile to act as a remote stereocontrol inductor in the Diels-Alder reaction with cyclopentadiene has been evaluated. High pressure conditions were required for the reactions of (S)-2-(p-tolylsulfinyl)styrenes 3-5 (E-1,2-disubstituted double bond) and 6-8 (1,1-disubstituted double bond). A good facial selectivity and total endo selectivity were attained with 1,1-disubstitued dienophiles, though the 1,2-disubstituted ones afforded poorer results. In contrast, (S)-[2-(p-tolylsulfinyl)phenyl] vinyl ketones 9-11 reacted readily at low temperature (-40 °C) with complete endo selectivity and high facial selectivity in the presence of Yb(OTf)3 as a chelating reagent of sulfinyl and carbonyl oxygen atoms. Concerning furan reactions, β-trifluoromethyl enone 14 afforded Diels-Alder adducts with high facial selectivity in the presence of the Lewis acid, but β-non-substituted enones 9 and 12 yielded products of furan conjugate addition to the double bond.
