1378429-91-4Relevant academic research and scientific papers
Ligand-free copper-catalyzed cross-coupling reaction of alkynes with aryl iodides and vinyl halides
Tsai, Wan-Ting,Lin, Yun-Yung,Chen, Yi-An,Lee, Chin-Fa
supporting information, p. 443 - 447 (2014/03/21)
A copper-catalyzed cross-coupling reaction of alkynes with aryl iodides is described. The system tolerates a broad range of functional groups and enables the sterically demanding substrates presented during the catalysis with only 5-10 mol% of Cu2O as the catalyst. Georg Thieme Verlag Stuttgart. New York.
Copper-catalyzed coupling of alkynes with alkenyl halides
Lin, Yun-Yung,Wang, Yu-Jen,Cheng, Jun-Hao,Lee, Chin-Fa
supporting information; experimental part, p. 930 - 934 (2012/06/04)
The synthesis of enynes from the coupling of terminal alkynes with alkenyl iodides and bromides is described. This system employs 1.0-5.0 mol% of CuI(Xantphos) as a catalyst. A variety of alkenyl iodides and bromides are coupled smoothly with terminal alkynes, affording enynes in good to excellent yields. Georg Thieme Verlag Stuttgart · New York.
Microwave-assisted copper-catalyzed cross-coupling reaction of alkynes with aryl iodides and vinyl halides
Tsai, Wen-Ting,Lin, Yun-Yung,Wang, Yu-Jen,Lee, Chin-Fa
supporting information; experimental part, p. 1507 - 1510 (2012/06/18)
The microwave-assisted, copper-catalyzed coupling of terminal alkynes with aryl iodides and vinyl halides is reported. In general, the reactions are completed in 10-30 min using 2-5 mol% [CuI(xantphos)] as a catalyst to provide the corresponding alkynes and enynes in good to excellent yields. A broad spectrum of aryl iodides, vinyl iodides, and bromides are coupled with aryl- and alkyl alkynes.
