1378469-98-7Relevant academic research and scientific papers
Studies on the synthesis of 2-alkyl-5-aryl-1,3,4-oxadiazolines from N-acylhydrazones
Marqués-López, Eugenia,Díez, Elena,Martín-Zamora, Eloísa,álvarez, Eleuterio,Fernández, Rosario,Lassaletta, José M.
supporting information; experimental part, p. 885 - 888 (2012/05/20)
Reaction of N-acylhydrazones with benzyloxyacetyl chloride in the presence of i-Pr2EtN affords new 1,3,4-oxadiazolines in excellent yields (72-95%), under mild reaction conditions and in short reaction times. The structures of the products were confirmed by single-crystal X-ray diffractometry. A plausible reaction mechanism is proposed. Georg Thieme Verlag Stuttgart · New York.
