1378490-54-0

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 89-98-5 2-chloro-benzaldehyde 
• 106-47-8 4-chloro-aniline 

Relevant academic research and scientific papers

Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators

The vitamin D receptor (VDR) is a nuclear hormone receptor that regulates cell proliferation, cell differentiation, and calcium homeostasis. The receptor is activated by vitamin D analogues that induce the disruption of VDR-corepressor binding and promote

VITAMIN D RECEPTOR - COREGULATOR INHIBITORS

Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactivator, for treating