137862-57-8

Basic information

• Product Name: Alanine Valsartan
• Synonyms: Alanine Valsartan
• CAS NO: 137862-57-8
• Molecular Formula: C22H24N5O3
• Molecular Weight: 406.45766
• Product Categories: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 137862-57-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Alanine Valsartan(CAS DataBase Reference)
• NIST Chemistry Reference: Alanine Valsartan(137862-57-8)
• EPA Substance Registry System: Alanine Valsartan(137862-57-8)

Safety Data

• Hazardous Substances Data: 137862-57-8(Hazardous Substances Data)

Usage

Uses

Alanine Valsartan is a Valsartan (V095750) impurity, a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

Relevant articles and documents

ACYL COMPOUNDS

Compounds of the formula STR1 in which R 1 is an aliphatic hydrocarbon radical which is unsubstituted or substituted by halogen or hydroxyl, or a cycloaliphatic or araliphatic hydrocarbon radical; X 1 is CO, SO 2, or--O--C(=O)--with the carbon atom of the carbonyl group being attached to the nitrogen atom shown in formula I; X 2 is a divalent aliphatic hydrocarbon radical which is unsubstituted or substituted by hydroxyl, carboxyl, amino, guanidino or a cycloaliphatic or aromatic radical, or is a divalent cycloaliphatic hydrocarbon radical, it being possible for a carbon atom of the aliphatic hydrocarbon radical to be additionally bridged by a divalent aliphatic hydrocarbon radical; R. sub.2 is carboxyl which, if desired, is esterified or amidated, substituted or unsubstituted amino, formyl which, if desired, is acetalized, 1H-tetrazol-5-yl, pyridyl, hydroxyl which, if desired, is etherified, S(O) m--R where m is 0, 1 or 2 and R is hydrogen or an aliphatic hydrocarbon radical, alkanoyl, unsubstituted or N-substituted sulfamoyl or PO n H 2 where n is 2 or 3; X 3 is a divalent aliphatic hydrocarbon; R 3 is carboxyl, 5-tetrazolyl, SO. sub.3 H, PO. sub.2 H 2, PO 3 H 2 or haloalkylsulfamoyl; and the rings A and B independently of one another are substituted or unsubstituted; in free form or in salt form, can be prepared in a manner known per se and can be used, for example, as medicament active ingredients.