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1378680-89-7

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1378680-89-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1378680-89-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,8,6,8 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1378680-89:
(9*1)+(8*3)+(7*7)+(6*8)+(5*6)+(4*8)+(3*0)+(2*8)+(1*9)=217
217 % 10 = 7
So 1378680-89-7 is a valid CAS Registry Number.

1378680-89-7Upstream product

1378680-89-7Downstream Products

1378680-89-7Relevant academic research and scientific papers

Design, synthesis and identification of novel colchicine-derived immunosuppressant

Chang, Dong-Jo,Yoon, Eun-Young,Lee, Geon-Bong,Kim, Soon-Ok,Kim, Wan-Joo,Kim, Young-Myeong,Jung, Jong-Wha,An, Hongchan,Suh, Young-Ger

scheme or table, p. 4416 - 4420 (2010/04/05)

Synthesis and biological evaluation of various colchicine analogues through the mixed-lymphocyte reaction (MLR), lymphoproliferation, and inhibitory effects on the inflammatory genes are described. In addition, a new series of immunosuppressive agents developed on the structural basis of colchicine, as well as their structure-activity relationships is reported. The most potent analogue 20a exhibited an excellent immunosuppressive activity on in vivo skin-allograft model, which is comparable to that of cyclosporin A.

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