137872-83-4 Usage
Molecular Weight
342.391 g/mol
Usage
Intermediate in the synthesis of various pharmaceuticals and organic compounds
Biological Activity
Potential to exhibit biological activity, suggesting potential applications in medicinal chemistry
Structure
Consists of a propenamide group attached to a quinolinyl and phenyl moiety
Versatility
Offers potential for further chemical modifications and derivatization
Safety
Requires careful handling and adherence to proper safety protocols in laboratory settings
Check Digit Verification of cas no
The CAS Registry Mumber 137872-83-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,8,7 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 137872-83:
(8*1)+(7*3)+(6*7)+(5*8)+(4*7)+(3*2)+(2*8)+(1*3)=164
164 % 10 = 4
So 137872-83-4 is a valid CAS Registry Number.
137872-83-4Relevant academic research and scientific papers
Substituted aminoquinolines as modulators of chemokine receptor activity
-
, (2008/06/13)
The present invention is directed to aminoquinolines of Formula I: STR1 (wherein R 1, R 2, R 3, and R 4 are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
Substituted 4,6-Diaminoquinolines as Inhibitors of C5a Receptor Binding
Lanza, Thomas J.,Durette, Philippe L.,Rollins, Thomas,Siciliano, Salvatore,Cianciarulo, Dana N.,et al.
, p. 252 - 258 (2007/10/02)
The anaphylatoxin C5a is implicated in a number of inflammatory diseases.It is a highly cationic protein with 13 of 74 amino acids being either arginine or lysine.A search focusing on positively charged molecules, particularly amine-containing functionali
