1378802-34-6

Basic information

• Product Name: 4-(3-Chloropyrazin-2-yl)-2-Methylbut-3-yn-2-ol
• Synonyms: 4-(3-Chloropyrazin-2-yl)-2-Methylbut-3-yn-2-ol
• CAS NO: 1378802-34-6
• Molecular Formula: C₉H₉ClN₂O
• Molecular Weight: 196.63356
• Mol File: 1378802-34-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(3-Chloropyrazin-2-yl)-2-Methylbut-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Chloropyrazin-2-yl)-2-Methylbut-3-yn-2-ol(1378802-34-6)
• EPA Substance Registry System: 4-(3-Chloropyrazin-2-yl)-2-Methylbut-3-yn-2-ol(1378802-34-6)

Safety Data

• Hazardous Substances Data: 1378802-34-6(Hazardous Substances Data)

Upstream product

• 4858-85-9 2,3-dichloropyrazine 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Downstream Products

• 55557-52-3 2-chloro-3-cyanopyrazine 

Relevant articles and documents

Synthesis method of 7-bromothieno [2, 3-B] pyrazine

The invention provides a preparation method of 7-bromothieno [2, 3-b] [1, 2, 4] thiadiazole. The invention discloses a synthetic method of 2, 3-B] pyrazine. Relating to the organic synthesis field, the preparation method comprises the following steps: reacting 2, 3-dichloropyrazine with 2-methyl-3-butyne-2-ol, cuprous iodide and triethylamine under the catalytic action of tetrakis (triphenylphosphine) palladium to generate 2-methyl-4-(3-chloropyrazine)-3-butyne-2-ol; 2-methyl-4-(3-chloropyrazine)-3-butyne-2-ol reacts with alkali to obtain 2-chloro-3-ethynylpyrazine, 2-chloro-3-ethynylpyrazinereacts with sodium sulfide nonahydrate to generate thieno [2, 3-B] pyrazine, and thieno [2, 3-B] pyrazine further reacts with N-bromosuccinimide to generate 7-bromothieno [2, 3-. The synthesis methodprovided by the invention has the advantages of easily available raw materials, mild reaction conditions, high selectivity, good operability of post-treatment, high yield and easiness in large-scale production.