1378848-02-2Relevant articles and documents
Aqueous photocatalytic oxidation of amoxicillin
Klauson,Babkina,Stepanova,Krichevskaya,Preis
, p. 39 - 45 (2010)
Aqueous photocatalytic oxidation (PCO) of amoxicillin (AMO), a β-lactam antibiotic, was experimentally studied. Degussa P25 titanium dioxide and visible light-sensitive sol-gel synthesized carbon- and iron-doped titania were used as photocatalysts. The efficiency of PCO dependent on initial AMO concentration and pH was established. A number of organic and inorganic by-products were determined allowing construction of a possible reaction pathway.
Electrochemical oxidation of amoxicillin on carbon nanotubes and carbon nanotube supported metal modified electrodes
Ferreira, Marta,Kuzniarska-Biernacka, Iwona,Fonseca, António M.,Neves, Isabel C.,Soares, Olívia S.G.P.,Pereira, Manuel F.R.,Figueiredo, José L.,Parpot, Pier
, p. 322 - 331 (2019/07/10)
The electrolysis of amoxicillin (AMX) was carried out on CNT, Pt/CNT and Ru/CNT modified electrodes based on Carbon Toray in 0.1 M NaOH, 0.1 M NaCl and 0.1 M Na2CO3/NaHCO3 buffer (pH 10) media with the aim of studying the significance of two factors, electrode material and pH, on the oxidative degradation and mineralization of AMX. For this purpose, the electrolysis products were identified by HPLC-MS and GC–MS, and quantified by HPLC-UV-RID and IC. The highest carbon mineralization efficiency, corresponding to 30% of the oxidized AMX, was found for Pt/CNT modified electrode in carbonate buffer medium. Regarding to the AMX conversion, the results show that the effect of pH is higher than that of the electrode material. Principal component analysis allowed to determine the experimental parameters vs. product distribution relationship and to elucidate the oxidation pathways for the studied electrodes. The results show that the hydroxylation of the aromatic ring and the nitrogen atom play an important role on the efficient degradation of AMX.
