1378851-20-7

Basic information

• Product Name: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole hydrochloride
• Synonyms: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole hydrochloride
• CAS NO: 1378851-20-7
• Molecular Weight: 396.124
• Mol File: 1378851-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole hydrochloride(1378851-20-7)
• EPA Substance Registry System: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole hydrochloride(1378851-20-7)

Safety Data

• Hazardous Substances Data: 1378851-20-7(Hazardous Substances Data)

Upstream product

• 1380167-24-7 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole methylsulfate 
• 139369-42-9 4-chloro-5-(2,3-dichlorophenoxy)-1,2-phenylenediamine 
• 68828-69-3 6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol 
• 118353-04-1 4-chloro-5-(2,3-dichlorophenoxy)-2-nitroaniline 
• 5462-30-6 N-(4,5-dichloro-2-nitrophenyl)acetamide 
• 576-24-9 2,3-dichlorophenol 

Downstream Products

• 68786-66-3 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzo[d]imidazole 

Relevant articles and documents

PROCESS FOR PREPARATION OF TRICLABENDAZOLE

The present invention discloses a method for preparing Triclabendazole comprising condensing N-(4,5-dichloro-2-nitrophenyl)acetamide with 2,3-dichlorophenol to obtain 4-chloro-5(2,3-dichlorophenoxy)-2-nitrophenyl acetamide and it to obtain 4- chloro-5(2,3-dichlorophenoxy)-2-nitroaniline; reducing 4-chloro-5(2,3- dichlorophenoxy)-2-nitroaniline in presence of Raney nickel to obtain 4-chloro-5- (2,3-dichlorophenoxy)benzene-l,2-diamine of; cyclising 4-chloro-5-(2,3- dichlorophenoxy)benzene-l,2-diamine in presence of carbondisulfide to obtain 6- chloro-5-(2,3-dichlorophenoxy)-lH-benzimidazole-2-thiol; methylating 6-chloro-5- (2,3-dichlorophenoxy)-lH-benzimidazole-2 -thiol using a methylating agent to obtain triclabendazole methanesulfonate salt; converting triclabendazole methanesulfonate salt to hydrochloride salt of Triclabendazole and hydrolysing it to obtain Triclabendazole.