137888-11-0

Basic information

• Product Name: TA 2005
• Synonyms: TA 2005;2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)-, monohydrochloride, (R-(R*,R*))-;8-Hydroxy-5-(1-hydroxy-2-(N-(2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)carbostyril hydrochloride;Carmoterol hydrochloride;Chf 4226.01;2(1H)-Quinolinone, 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-Methoxyphenyl)-1-Methylethyl ]aMino]ethyl]-, Monohydrochloride;8-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone hydrochloride;CarMoterol hcl
• CAS NO: 137888-11-0
• Molecular Formula: C21H24N2O4.ClH
• Molecular Weight: 404.892
• EINECS: 1312995-182-4
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 137888-11-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 142-144°C
• Boiling Point: 649.1oC at 760mmHg
• Flash Point: 346.4oC
• Appearance: Light Beige to Beige Solid
• Density: g/cm³
• Vapor Pressure: 9.75E-18mmHg at 25°C
• Storage Temp.: -20?C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)
• Stability: Hygroscopic
• CAS DataBase Reference: TA 2005(CAS DataBase Reference)
• NIST Chemistry Reference: TA 2005(137888-11-0)
• EPA Substance Registry System: TA 2005(137888-11-0)

Safety Data

• Hazardous Substances Data: 137888-11-0(Hazardous Substances Data)

Usage

Description

TA 2005, also known as Carmoterol, is a highly potent β2-selective adrenoceptor agonist derived from hydrolyzable tannins found in gall nuts and various plant sources. It possesses a yellow solid appearance and exhibits a long-lasting bronchodilating effect. Its chemical properties enable interactions with biopolymers and macromolecules, making it a promising pharmaceutical candidate for various applications.

Uses

Used in Pharmaceutical Industry:
TA 2005 is used as a bronchodilator for treating respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Its β2-selective adrenoceptor agonist property allows it to effectively relax the smooth muscles in the airways, providing relief from bronchoconstriction and improving lung function.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, if TA 2005 were to have similar properties to Gallotannin, it could potentially be employed as an anticancer agent. It could modulate various oncological signaling pathways, exerting inhibitory effects on tumor growth and progression, and demonstrating synergistic anticancer effects when combined with conventional chemotherapeutic drugs.
Used in Drug Delivery Systems:
Similarly, if TA 2005 shared properties with Gallotannin, it could be utilized in the development of novel drug delivery systems to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles could be employed as carriers for TA 2005 delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.

InChI:InChI=1/C21H24N2O4.ClH/c1-13(11-14-3-5-15(27-2)6-4-14)22-12-19(25)16-7-9-18(24)21-17(16)8-10-20(26)23-21;/h3-10,13,19,22,24-25H,11-12H2,1-2H3,(H,23,26);1H/t13-,19+;/m1./s1