13792-27-3

Upstream product

• 5871-17-0 potassium O,O'-diethylthiophosphate 
• 103-63-9 1-phenyl-2-bromoethane 
• 762-04-9 phosphonic acid diethyl ester 
• 4410-99-5 2-mercaptophenylethane 

Relevant academic research and scientific papers

Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes

An efficient Cs2CO3-catalyzed oxidative coupling of thiols with phosphonates and arenes that uses molecular oxygen as the oxidant is described. These reactions provide not only a novel alkali metal salt catalyzed aerobic oxidation, but also an efficient approach to thiophosphates and sulfenylarenes, which are ubiquitously found in pharmaceuticals and pesticides. The reaction proceeds under simple and mild reaction conditions, tolerates a wide range of functional groups, and is applicable to the late-stage synthesis and modification of bioactive molecules.

A thiophosphate synthetic method of compound and the method in a plurality of pharmaceutical application in the synthesis of (by machine translation)

The invention discloses a having the general formula (III) of the thiophosphate synthetic method of compound, the purpose is to provide a novel, condition is simple, easy to industrial production of the thiophosphate synthetic method of compound. The method is to have the general formula (I) of the organophosphorus oxygen apperception compound having the general formula (II) with a mercaptan or phenyl-sulfhydryl apperception compound mixed, under the effects of catalyst, obtained by the reaction of the formula (III) of the thiophosphate compound. The method of the invention, can be cheap efficient synthesis of thiophosphate compounds, in actual production will have extensive application prospect. (by machine translation)

A facile and efficient microwave-mediated S-alkylation of thiophosphates

A convenient, highly efficient, safe microwave-mediated S- alkylation of O,O'-dialkyl thiophosphate has been reported. Clean and rapid S-alkylation of thiophosphates can be achieved by irradiating a mixture of dialkylthiophosphate salt and alky! halide under microwave for a brief period. Alkylation occurs exclusively at sulfur to provide S-alkylated products. Through a simple workup, pure compounds have been obtained easily in good yields.

A convenient method for the synthesis of phosphorothioates and their anticholinesterase activites

A simple, efficient, and general method has been developed for the synthesis of phosphorothioates through a one-pot reaction of alkyl halides with the mixture of diethyl phosphite in the presence of NH4OAc/S/CaO under solvent-free conditions. T

A simple and new method for the synthesis of thiophosphates

A simple, efficient, and general method has been developed for the synthesis of thiophosphates through a one-pot reaction of alkyl halides with the mixture of diethyl phosphite in the presence of ammonium acetate/sulfur and acidic alumina under solvent-fr