137927-36-7Relevant academic research and scientific papers
Syntheses of 1-aryl-2-trifluoromethylbenzimidazoles via electrochemically prepared p-benzoquinone imines
Uneyama, Kenji,Kobayashi, Masafumi
, p. 5981 - 5982 (1991)
Electrooxidation of N-(4-methoxyphenyl)-N′-aryl-2,2,2-trifluoethanimidamides 1 in an MeCN-H2O-NaClO4-(C)-(Pt) system affords p-benzoquinone imines 2 which are converted to 1-aryl-2-trifluoromethylbenzimidazoles 3 by acid catalyzed cy
N1-(4-Oxo-2,5-cyclohexadien-1-ylidene)-N2-substituted-2,2,2-trifluoroethanimidamides (p-Benzoquinone Imine Derivatives): Syntheses of Trifluoromethylated 6-Hydroxybenzimidazoles and Spiro Dienone Diazacarbocycles
Kobayashi, Masafumi,Uneyama, Kenji,Hamada, Noritaka,Kashino, Setsuo
, p. 6402 - 6407 (2007/10/03)
Lewis acid-catalyzed intramolecular cyclization of N1-(4-oxo-2,5-cyclohexadien-1-ylidene)-N2-substituted-2,2,2-trifluoroethanimidamides (p-benzoquinone imine derivatives, 1) prepared by electrooxidation of N-(4-methoxyphenyl)-N'-substituted-2,2,2-trifluoroethanimidamides 2 occurred to give 1-substituted-2-(trifluoromethyl)-6-hydroxybenzimidazoles 3.Alternatively, thermal cyclization of 1 gave spiro dienone diazacarbocycles 9 and 10, which converted into diazepine 12 via a dienone-phenol rearrangement.
