1379304-63-8Relevant academic research and scientific papers
Synthesis of 5-and 7-fluoroquinazolin-4(1H)-ones
Layeva,Nosova,Lipunova,Trashakhova,Charushin
, p. 1821 - 1827 (2007)
5-Fluoroquinazoline-2,4-diones and their 2-thio analogs were obtained from 6-fluoroanthranilic acid. Two convenient routes to 5-fluoroquinazolin-4-ones involved cyclocondensation of 6-fluoroanthranilamide with acid chlorides (anhydrides) or with aromatic (heterocyclic) aldehydes. A method for the synthesis of 7-fluoroquinazolin-4-one from 2,4-difluorobenzoic acid was proposed.
