1379420-89-9Relevant academic research and scientific papers
N-Hydroxy-(4-oxime)-cinnamide: A versatile scaffold for the synthesis of novel histone deacetilase (HDAC) inhibitors
Giannini, Giuseppe,Marzi, Mauro,Pezzi, Riccardo,Brunetti, Tiziana,Battistuzzi, Gianfranco,Marzo, Maria Di,Cabri, Walter,Vesci, Loredana,Pisano, Claudio
scheme or table, p. 2346 - 2349 (2009/12/07)
With the aim to discover novel HDAC inhibitors with high potency and good safety profiles, we have designed a small library based on a N-hydroxy-(4-oxime)-cinnamide scaffold. We describe the synthesis of these novel compounds and some preliminary in vitro
