1379458-07-7Relevant academic research and scientific papers
Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues
Al-Suwaidan, Ibrahim A.,Abdel-Aziz, Naglaa I.,El-Azab, Adel S.,El-Sayed, Magda A.-A.,Alanazi, Amer M.,El-Ashmawy, Mahmoud B.,Abdel-Aziz, Alaa A.-M.
, p. 679 - 687 (2015/07/27)
A series of 2-(arylidene)-1-(4-chlorophenyl)-4,4,4-trifluorobutane-1,3-diones (2-4), 4-(arylidene)-3-(4-chlorophenyl)-5-(trifluoromethyl)-4H-pyrazoles (5-7), 1-(4-chlorophenyl)-4,4,4-trifluoro-2-(2-(aryl)hydrazono)butane-1,3-diones (8, 9), 3-(4-chlorophen
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
El-Sayed, Magda A.-A.,Abdel-Aziz, Naglaa I.,Abdel-Aziz, Alaa A.-M.,El-Azab, Adel S.,Eltahir, Kamal E.H.
, p. 3306 - 3316 (2012/07/14)
New pyrazole and pyrazoline derivatives have been synthesized and their ability to inhibit ovine COX-1/COX-2 isozymes was evaluated using in vitro cyclooxygenase (COX) inhibition assay. Among the tested compounds, N-((5-(4-chlorophenyl)-1-phenyl-3-(triflu
