1379520-63-4Relevant academic research and scientific papers
The design, synthesis and antimicrobial activity of new biquinoline derivatives
Shah, Nirav K.,Shah, Nimesh M.,Patel, Manish P.,Patel, Ranjan G.
, p. 279 - 286 (2012/06/01)
A simple and efficient method has been developed for the synthesis of some novel biquinoline derivatives bearing a thiazole moiety through a onepot three-component condensation of 2-chloro-3-formylquinolines, ethyl cyanoacetate and a β-enaminone using a catalytic amount of piperidine in refluxing ethanol. These molecules were evaluated in vitro for their antibacterial and antifungal activity. Most of the compounds exhibited moderate antibacterial and antifungal activity against all the tested strains.
