1379581-10-8Relevant academic research and scientific papers
Diastereoselective 1,3-dipolar cycloaddition of pyrylium ylides with chiral enamides
Tchabanenko, Kirill,Sloan, Colleen,Bunetel, Yves-Mael,Mullen, Philip
experimental part, p. 4215 - 4219 (2012/07/03)
Chiral enamides 5f-i were found to react with pyrylium ylides to give cycloadducts 6d-i in good yields with an excellent level of stereoselectivity. The chiral auxiliary was successfully removed on hydrogenolysis of compound 6f in continuous flow (H-Cube)
