1379595-04-6

Basic information

• Product Name: (2S,3S,5R)-3-(4-methyl-iinidazol-1-ylmethyl)-3-methyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester
• Synonyms: (2S,3S,5R)-3-(4-methyl-iinidazol-1-ylmethyl)-3-methyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester
• CAS NO: 1379595-04-6
• Molecular Weight: 479.557
• Mol File: 1379595-04-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,5R)-3-(4-methyl-iinidazol-1-ylmethyl)-3-methyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,5R)-3-(4-methyl-iinidazol-1-ylmethyl)-3-methyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(1379595-04-6)
• EPA Substance Registry System: (2S,3S,5R)-3-(4-methyl-iinidazol-1-ylmethyl)-3-methyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(1379595-04-6)

Safety Data

• Hazardous Substances Data: 1379595-04-6(Hazardous Substances Data)

Upstream product

• 1379595-03-5 (2S,3S,5R)-3-(4-methyl-imidazol-1-ylmethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 85573-73-5 2β-(chloro)methyl-2α-methyl-6,6-dihydropenam-3α-carboxylic acid benzhydryl ester 

Downstream Products

• 1379595-05-7 C₂₆H₂₈N₃O₅S⁽¹⁺⁾*I^(1-) 

Relevant articles and documents

COMPOUNDS AND THEIR USE

Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as β -lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of β-lactamases. These compounds restore/potentiate the activities of β-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting β-lactamases. Formula (I)