1379596-16-3Relevant academic research and scientific papers
An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer
Jordan, Peter A.,Miller, Scott J.
experimental part, p. 2907 - 2911 (2012/05/20)
Selective: The deoxygenation of simple and complex natural products employing a readily synthesized phosphoramidite and tetrazole catalysts can be executed as a two-step process, without the need to isolate intermediate deoxygenation precursors. Furthermore, a peptide-based tetrazole catalyst controls the site selectivity of deoxyerythromycin synthesis (see scheme), thus overcoming the notorious challenges with unprotected erythromycin A. Copyright
