1379604-76-8

Basic information

• Product Name: 4-(4-chlorophenyl)-1-[(S)-3,4-dihydroxybutyl]-3-(3-{4-[4-(4-{[(R)-4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitrophenylsulfonamido)phenyl]piperazin-1-yl}phenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide
• CAS NO: 1379604-76-8
• Molecular Weight: 1107.84
• Mol File: 1379604-76-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-1-[(S)-3,4-dihydroxybutyl]-3-(3-{4-[4-(4-{[(R)-4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitrophenylsulfonamido)phenyl]piperazin-1-yl}phenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-1-[(S)-3,4-dihydroxybutyl]-3-(3-{4-[4-(4-{[(R)-4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitrophenylsulfonamido)phenyl]piperazin-1-yl}phenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide(1379604-76-8)
• EPA Substance Registry System: 4-(4-chlorophenyl)-1-[(S)-3,4-dihydroxybutyl]-3-(3-{4-[4-(4-{[(R)-4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitrophenylsulfonamido)phenyl]piperazin-1-yl}phenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide(1379604-76-8)

Safety Data

• Hazardous Substances Data: 1379604-76-8(Hazardous Substances Data)

Upstream product

• 140-53-4 p-chlorobenzyl cyanide 
• 170911-92-9 4-(4-aminophenyl)-1-t-butyloxycarbonylpiperazine 
• 6668-56-0 4-fluoro-3-nitrobenzene-1-sulfonyl chloride 
• 696-41-3 m-iodobenzaldehyde 
• 1376191-12-6 t-butyl 4-[4-(4-fluoro-3-nitrophenylsulfonamido)phenyl]piperazine-1-carboxylate 
• 1376190-98-5 (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(3-iodophenyl)-1H-pyrrole-2-carboxylate 
• 1376190-93-0 ethyl 4-(4-chlorophenyl)-3-(3-iodophenyl)-1H-pyrrole-2-carboxylate 
• 1376190-51-0 (R)-4-{[4-(dimethylamino)-1-(phenylthio)but-2-yl]amino}-3-nitro-N-[4-(piperazin-1-yl)phenyl]benzenesulfonamide 
• 1376191-03-5 (S)-4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-(3-iodophenyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-2-carboxamide 

Relevant articles and documents

BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME

Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.