1379665-21-0

Basic information

• Product Name: N-(2-bromo-5-methylphenyl)-N-methyl-2-fluoro-2-(2-chlorophenyl)acetamide
• CAS NO: 1379665-21-0
• Molecular Weight: 370.649
• Mol File: 1379665-21-0.mol

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-5-methylphenyl)-N-methyl-2-fluoro-2-(2-chlorophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-5-methylphenyl)-N-methyl-2-fluoro-2-(2-chlorophenyl)acetamide(1379665-21-0)
• EPA Substance Registry System: N-(2-bromo-5-methylphenyl)-N-methyl-2-fluoro-2-(2-chlorophenyl)acetamide(1379665-21-0)

Safety Data

• Hazardous Substances Data: 1379665-21-0(Hazardous Substances Data)

Upstream product

• 54879-20-8 2-bromo-3-methylaniline 
• 74-88-4 methyl iodide 

Downstream Products

• 1379665-37-8 (R)-3-fluoro-1,6-dimethyl-3-(2-chlorophenyl)-indolin-2-one 

Relevant articles and documents

Synthesis of 3-fluoro-3-aryl oxindoles: Direct enantioselective α arylation of amides

Modus operandi: Catalytic access to the title compounds through a new asymmetric α-arylation protocol is reported (see scheme). These products are formed in good yields and excellent enantioselectivities by using a new and easily synthesized chiral N-heterocyclic carbene (NHC) ligand. Advanced DFT calculations reveal the properties of the NHC ligand and the mode of operation of the catalyst. Copyright