13797-62-1

Basic information

• Product Name: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID
• Synonyms: AKOS BBS-00007904;2-(2-METHYL-1,3-THIAZOL-4-YL)ACETIC ACID;(2-METHYL-THIAZOL-4-YL)-ACETIC ACID;(2-METHYL-1,3-THIAZOL-4-YL)ACETIC ACID;CHEMBRDG-BB 4400881;IFLAB-BB F0848-0152;(2-METHYL-THIAZOL-4-YL)-ACETIC【MFCD02669593】;(2-methyl-1,3-thiazol-4-yl)acetic acid(SALTDATA: FREE)
• CAS NO: 13797-62-1
• Molecular Formula: C₆H₇NO₂S
• Molecular Weight: 157.19
• Mol File: 13797-62-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 125-126 °C
• Boiling Point: 304.9 °C at 760 mmHg
• Flash Point: 138.2 °C
• Appearance: /
• Density: 1.356 g/cm³
• Vapor Pressure: 0.000372mmHg at 25°C
• PKA: 4.79±0.10(Predicted)
• CAS DataBase Reference: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(13797-62-1)
• EPA Substance Registry System: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(13797-62-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 13797-62-1(Hazardous Substances Data)

Usage

Description

(2-METHYL-THIAZOL-4-YL)-ACETIC ACID, also known as Zomig, is a pharmaceutical compound belonging to the thiazole class of organic molecules. It is a derivative of thiazole with a methyl group attached to the second carbon atom and features an acetic acid component, which acts as a weak acid in chemical reactions. (2-METHYL-THIAZOL-4-YL)-ACETIC ACID possesses both pharmaceutical and biological properties, making it a valuable asset in the management of migraines.

Uses

Used in Pharmaceutical Industry:
(2-METHYL-THIAZOL-4-YL)-ACETIC ACID is used as a medication for the treatment of migraines. It functions by narrowing blood vessels in the brain and reducing the chemicals in the body that can trigger headaches, nausea, and other migraine symptoms, providing relief to patients suffering from this condition.

InChI:InChI=1/C6H7NO2S/c1-4-7-5(3-10-4)2-6(8)9/h3H,2H2,1H3,(H,8,9)/p-1

Upstream product

• 638-07-3 ethyl (2-chloroaceto)acetate 
• 857982-41-3 thiazole-2,4-diyl-di-acetic acid diethyl ester 
• 37128-24-8 ethyl (2-methyl-1,3-thiazol-4-yl)acetate 

Downstream Products

• 121357-04-8 2-(2-methylthiazol-4-yl)ethanol 
• 1444405-05-3 C₂₃H₂₇N₇O₂S 
• 1277098-56-2 benzyl-2-[(2-methylthiazol-4-yl)methyl]-1H-benzoimidazole-5-carboxylic acid 
• 1277098-54-0 methyl 1-benzyl-2-[(2-methylthiazol-4-yl)methyl]-1H-benzoimidazole-5-carboxylate 
• 408367-58-8 N-(4-{[(2-Methyl-1,3-thiazol-4-yl)acetyl]amino}phenyl)-4'-(trifluoromethyl)-1,1'-biphenyl-2-carboxamide 
• 541-58-2 2,4-dimethylthiazole 
• 15719-64-9 methylammonium carbonate 

Relevant articles and documents

Ramoplanin derivatives possessing antibacterial activity

Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

Diphosphonate derivatives, pharmaceutical compositions and methods of use for calcium disturbances

The present invention produces alkyldiphosphonic acid derivative of the general formula: STR1 wherein Het is a heteroaromatic five-membered ring containing to 3 heteroatoms which can be partly hydrogenated and optionally substituted one or more times by alkyl, alkoxy, phenyl, cyclohexyl, cyclohexylmethyl, halogen or amino, and two adjacent alkyl substituents can together also form a ring, Y is a hydrogen atom or a lower alkyl radical, X is a hydrogen atom, a hydroxyl group or an amino group optionally substituted by lower alkyl and R is a hydrogen atom or a lower alkyl radical, with the proviso that Het is not a pyrazole ring; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the prepearation of these compounds and pharmaceutical compositions containing them useful for the treatment or prophylaxis of calcium metabolism disturbances or disease as for example osteoporosis, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis osteoarthritis or degenerative arthrosis.