1379792-80-9

Basic information

• Product Name: 5,6-diphenyl-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile
• Synonyms: 5,6-diphenyl-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile
• CAS NO: 1379792-80-9
• Molecular Weight: 321.341
• Mol File: 1379792-80-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6-diphenyl-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-diphenyl-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile(1379792-80-9)
• EPA Substance Registry System: 5,6-diphenyl-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile(1379792-80-9)

Safety Data

• Hazardous Substances Data: 1379792-80-9(Hazardous Substances Data)

Upstream product

• 56413-95-7 2,3-dichloro-5,6-dicyanopyrazine 
• 536-74-3 phenylacetylene 
• 36023-64-0 2,3-dioxo-1,2,3,4-tetrahydropyrazine-5,6-dicarbonitrile 

Relevant articles and documents

Highly efficient synthesis of 5,6-disubstituted-5H-pyrrolo[2,3-b]pyrazine- 2,3-dicarbonitriles through a one-pot palladium-catalyzed coupling reaction/cyclization in water

A highly efficient one-pot synthesis of 5,6-disubstituted-5H-pyrrolo[2,3-b] pyrazine-2,3-dicarbonitriles is presented. The reaction of 5-(alkyl-arylamino)- 6-chloropyrazine-2,3-dicarbonitriles with phenylacetylene, catalyzed by Pd-Cu, in the presence of SDS as the surfactant in water, leads to the desired products in good-to-high yields.