1379799-76-4Relevant academic research and scientific papers
An efficient and general iron-catalyzed one-pot synthesis of furans via α-hydroxy ketones and activated alkynes
Cao, Hua,Zhan, Haiying,Wu, Jianyong,Zhong, Haiping,Lin, Yuanguang,Zhang, Hong
, p. 2318 - 2322 (2012)
A new practical and economical process for the synthesis of substituted furan derivatives has been developed by an FeCl3-catalyzed reaction of α-hydroxy ketones with activated alkynes. This methodology represents a highly efficient synthetic route to electron-deficient furans for which catalytic approaches are scarce. Furthermore, this transformation is associated with readily available substrates, good yields, and mild conditions. An efficient iron-catalyzed one-pot synthesis of polysubstituted furans has been developed from electron-deficient alkynes and α-hydroxy ketones under mild reaction conditions. This green and eco-friendly system has shown high catalytic activity in the synthesis of furan derivatives. The yields are good, and the scope of substrates is wide.
CuO/CNTs-catalyzed heterogeneous process: A convenient strategy to prepare furan derivatives from electron-deficient alkynes and α-hydroxy ketones
Cao, Hua,Jiang, Huan-Feng,Zhou, Xiao-Song,Qi, Chao-Rong,Lin, Yuan-Guang,Wu, Jian-Yong,Liang, Qi-Mei
, p. 2710 - 2714 (2012/11/07)
As heterogeneous catalysts and nanoparticle support materials, CNTs have attracted great interest in organic chemistry. This paper reports facile CuO/CNTs-catalyzed cyclization to form furan derivatives from electron-deficient alkynes and α-hydroxy ketones. It represents a facile synthetic route, and the eco-friendly catalyst can be easily separated by filtration and reused.
