1380098-27-0Relevant academic research and scientific papers
Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins
McCarthy, Anna R.,Pirrie, Lisa,Hollick, Jonathan J.,Ronseaux, Sebastien,Campbell, Johanna,Higgins, Maureen,Staples, Oliver D.,Tran, Fanny,Slawin, Alexandra M.Z.,Lain, Sonia,Westwood, Nicholas J.
, p. 1779 - 1793 (2012/04/17)
The tenovins are small molecule inhibitors of the NAD+-dependent family of protein deacetylases known as the sirtuins. There remains considerable interest in inhibitors of this enzyme family due to possible applications in both cancer and neuro
