1380168-28-4Relevant articles and documents
HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF
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Page/Page column 69-70, (2012/06/16)
Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits.