138019-60-0

Upstream product

• 62-23-7 4-nitro-benzoic acid 
• 833-63-6 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1448543-90-5 C₃₀H₁₈N₈NiO₆S₂ 
• 1448543-94-9 C₃₀H₁₈N₈O₆S₂Sn 
• 1448543-91-6 C₃₀H₁₈CuN₈O₆S₂ 
• 1448543-93-8 C₃₀H₁₈CdN₈O₆S₂ 
• 1448543-92-7 C₃₀H₁₈N₈O₆S₂Zn 

Relevant academic research and scientific papers

Synthesis, characterization and preliminary in vitro antibacterial screening activity of metal complexes derivatives of 2-{[5-(4-nitrophenyl)-1,3, 4-thiadiazol-2-ylimino]methyl}phenol

A total of five new metal complexes derivatives of 2-{[5-(4-nitrophenyl)-1, 3,4-thiadiazol-2-ylimino]methyl}phenol (HL) with the metal ions [Ni(II), Cu(II), Zn(II), Cd(II) and Sn(II)] have been successfully prepared in alcoholic medium. The complexes obtained are characterized quantitatively and qualitatively by using microelemental analysis, FTIR spectroscopy, UV-visible spectroscopy, mass spectroscopy, 1H and 13C NMR, magnetic susceptibility and conductivity measurements. From the spectral study, all the complexes obtained as monomeric structure and the metals centre moieties are four-coordinated with distorted tetrahedral geometry except Cu(II) complex which existed as a distorted square planar geometry. The preliminary in vitro antibacterial screening activity revealed that complexes 1-5 showed moderate activity against tested bacterial strains and slightly higher compared to the parent ligand.

Synthesis of 2-N-salicylidene-5-(substituted)-1,3,4-thiadiazole as potential antimicrobial agents

Several new 2,5-disubstituted derivatives of 1,3,4-thiadiazoles containing imine moiety were obtained from cyclization of thiosemicarbazide and corresponding p-substituted carboxylic acid in phosphorus oxychloride then the resulted products were reacted w