138022-04-5

Basic information

• Product Name: TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE
• Synonyms: TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE;tert-butyl methyl(4-piperidinylmethyl)carbamate(SALTDATA: FREE);N-Methyl-N-(4-piperidinylmethyl)-carbamic acid 1,1-dimethylethyl ester;tert-butyl methyl(4-piperidinylmethyl)carbamate;4-[(N-Boc-N-MethylaMino)Methyl]piperidine;CarbaMic acid, Methyl(4-piperidinylMethyl)-, 1,1-diMethylethyl ester;tert-butyl N-Methyl-N-(piperidin-4- ylMethyl)carbaMate;CarbaMic acid, N-Methyl-N-(4-piperidinylMethyl)-, 1,1-diMethylethyl ester
• CAS NO: 138022-04-5
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.33
• Mol File: 138022-04-5.mol

Chemical Properties

• Boiling Point: 306.014 °C at 760 mmHg
• Flash Point: 138.873 °C
• Appearance: /
• Density: 0.978 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.464
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.51±0.10(Predicted)
• CAS DataBase Reference: TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE(138022-04-5)
• EPA Substance Registry System: TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE(138022-04-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 138022-04-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE is used as a reagent for the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE is utilized as a key component in the research and development of novel pharmaceuticals, thanks to its chemical properties that facilitate the creation of new drug candidates.
Used in Antiviral and Antibacterial Drug Development:
TERT-BUTYL METHYL(PIPERIDIN-4-YLMETHYL)-CARBAMATE has shown potential as a drug candidate, particularly for its possible applications as an antiviral and antibacterial agent. This potential is currently under investigation, with further research required to fully explore its capabilities and effectiveness in these areas.

InChI:InChI=1/C12H24N2O2/c1-12(2,3)16-11(15)14(4)9-10-5-7-13-8-6-10/h10,13H,5-9H2,1-4H3

Downstream Products

• 1350918-33-0 tert-butyl (1-(2-fluoro-6-nitrophenyl)piperidin-4-yl)methyl(methyl)carbamate 
• 1350918-34-1 tert-butyl ((1-(2-amino-6-fluorophenyl)piperidin-4-yl)methyl)(methyl)carbamate 
• 1350918-35-2 tert-butyl ((1-(2-fluoro-6-(4-(2-methylpyridin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carboxamido)phenyl)piperidin-4-yl)methyl)(methyl)carbamate 
• 1350916-79-8 N-(3-fluoro-2-(4-((methylamino)methyl)-1-piperidinyl)phenyl)-4-(2-methyl-4-pyridinyl)-1H-imidazole-2-carboxamide 

Relevant articles and documents

ORALLY ACTIVE RENIN INHIBITORS

This invention relates to compounds of the formula STR1 wherein Q, Z, D, E, R 3, R 4, R 5 and R 6 are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.

Orally active renin inhibitors

This invention relates to compounds of the formula wherein Q, Z, D, E, R3, R?, R? and R? are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.