138022-86-3

Basic information

• Product Name: 1-Azetidin-3-yl-piperidine
• Synonyms: 1-Azetidin-3-yl-piperidine;1-(3-AZETIDINYL)PIPERIDINE;N-(3-AZETIDINYL)PIPERIDINE;1-(3-azetidinyl)piperidine(SALTDATA: 2HCl);3-Piperidinoazetidine;1-Azetidin-3-yl-piperidine hydrochloride
• CAS NO: 138022-86-3
• Molecular Formula: C₈H₁₆N₂
• Molecular Weight: 140.23
• Product Categories: Heterocycles series
• Mol File: 138022-86-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 216.5°C at 760 mmHg
• Flash Point: 92.4°C
• Appearance: /
• Density: 1.014g/cm³
• Vapor Pressure: 0.14mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Azetidin-3-yl-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azetidin-3-yl-piperidine(138022-86-3)
• EPA Substance Registry System: 1-Azetidin-3-yl-piperidine(138022-86-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 138022-86-3(Hazardous Substances Data)

Usage

General Description

1-Azetidin-3-yl-piperidine is a chemical compound with the molecular formula C10H20N2. It is a heterocyclic compound consisting of a piperidine ring fused to an azetidine ring. 1-Azetidin-3-yl-piperidine has been studied for its potential pharmacological properties, particularly as a potential drug candidate for various medical applications. The unique structure of 1-Azetidin-3-yl-piperidine makes it an interesting target for further research and development, and it may have potential applications in the fields of medicine, pharmaceuticals, and chemical synthesis. Further studies are needed to fully understand the properties and potential uses of this compound.

InChI:InChI=1/C8H16N2/c1-2-4-10(5-3-1)8-6-9-7-8/h8-9H,1-7H2

Upstream product

• 223381-52-0 1-benzylazetidin-3-ylpiperidine 

Relevant articles and documents

Synthesis of new quinolone antibiotics utilizing azetidine derivatives obtained from 1-azabicyclo[1.1.0]butane

A series of 3-sulfenylazetidine derivatives 5a-f were synthesized via the ring-opening reactions of 1-azabicyclo[ 1.1.0]butane (ABB, 3) with thiols 4a-f in 50-92% yields. Treatment of ABB (3) with aromatic amines 9a-e and dibenzylamine (9f) in the presence of Mg(ClO4)2 afforded the corresponding 3-aminoazetidine derivatives 10a-f in 24-65% yields. N-Benzyl-3-bromoazetidine (13), which was obtained by the reaction of ABB (3) with benzyl bromide, gave 3-aliphatic amino-substituted azetidine derivatives 15a, b. Novel fluoroquinolones 7a-f, 11a-f, 16a, b and 25a-c were obtained by the introduction of these azetidine derivatives into the C7 position of a quinolone nucleus 6 and N1-heterocyclic quinolones 21a-c in 21-83% yields. Some of them exhibited a greater antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) in comparison with that of clinically used fluoroquinolone, levofloxacin (LVFX).