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Anhydrotetracycline hydrochloride is a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions, resulting in the aromatization of the B ring. It is a yellow to bright yellow powder and is considered biologically active, although it exhibits no antibiotic activity. Anhydrotetracycline hydrochloride is an important standard for monitoring tetracycline stability and is thought to be responsible for aspects of tetracycline toxicity.

13803-65-1

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13803-65-1 Usage

Uses

Used in Bacterial Expression Systems:
Anhydrotetracycline hydrochloride is used as a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems for tetracycline-dependent gene expression in bacterial expression systems. It binds the Tet repressor 35-fold more strongly than Tet, allowing for more effective control of gene expression.
Used in Monitoring Tetracycline Stability:
Anhydrotetracycline hydrochloride is used as an important standard for monitoring the stability of tetracycline in various applications, as it is a degradation product formed under acidic conditions.
Used in Eukaryotic Cell Research:
Anhydrotetracycline hydrochloride is used in eukaryotic cell research to study its effects on cell growth, as the concentration that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR. This suggests that it may have potential applications in understanding and manipulating cellular processes.

Check Digit Verification of cas no

The CAS Registry Mumber 13803-65-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,0 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13803-65:
(7*1)+(6*3)+(5*8)+(4*0)+(3*3)+(2*6)+(1*5)=91
91 % 10 = 1
So 13803-65-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-26,30-31H,7,23H2,1-3H3/p+1/t11-,16-,22-/m0/s1

13803-65-1 Well-known Company Product Price

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  • USP

  • (1035708)  Anhydrotetracyclinehydrochloride  United States Pharmacopeia (USP) Reference Standard

  • 13803-65-1

  • 1035708-25MG

  • 14,500.98CNY

  • Detail

13803-65-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ANHYDROTETRACYCLINE HYDROCHLORIDE

1.2 Other means of identification

Product number -
Other names (4aS)-4c-dimethylamino-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-(4ar,12ac)-1,4,4a,5,12,12a-hexahydro-naphthacene-2-carboxylic acid amide,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13803-65-1 SDS

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