13803-74-2

Usage

Uses

Different sources of media describe the Uses of 13803-74-2 differently. You can refer to the following data:
1. 1,3-Dimethylpentylamine is useful in composition in treating hypertrophied and hyperplastic gums which showed a significant reduction in swelling.
2. Methylhexanamine (hydrochloride) is a simple aliphatic amine that was once marketed as a nasal decongestant (Forthane) but is now sold as a bodybuilding supplement (Floradrene, Geranamine). It is also sold as a mild stimulant in the form of party pills and has been reported to cause cerebral hemorrhage in a case report. While little is known about its mode of action, methylhexanamine interferes in immunoassays for amphetamines, presumably because of the common ethylamine structure. 4-Methyl-2-hexanamine hydrochloride is intended for forensic or research purposes.[Cayman Chemical]

Chemical Properties

White Solid

Biochem/physiol Actions

Methylhexanamine is a naturally substance isolated from Pelargonium graveolen. It is a component of geranium oil. Methylhexanamine is a sympathomimentic that increase levels of norepinephrine in the synaptic cleft.

Synthesis

At room temperature, 800 mL absolute ethanol was added into a 2 L three neck flask, stirred, and 35.38 g (1.538 mol) of metal sodium was added in batches to obtain a colorless transparent liquid. Cool slightly, add 200g (1.537 rnol) of ethyl acetoacetate, continue heating slowly, and add 232g (1.693 mol) of 2-bromobutane drop under weak reflux. Continue heating and react for 8 h at 80~84 ℃. Stop heating, cool naturally to room temperature, leave it still, filter by suction, and concentrate the yellow green filtrate under reduced pressure to obtain 241.4 g of 1,3-Dimethylpentanamine Hydrochloride with light yellow viscous solid in 84.3% yield.