138030-54-3Relevant academic research and scientific papers
The synthesis and structure-activity relationship of 4-benzimidazolyl- piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists
Ting, Pauline C.,Lee, Joe F.,Albanese, Margaret M.,Wu, Jie,Aslanian, Robert,Favreau, Leonard,Nardo, Cymbelene,Korfmacher, Walter A.,West, Robert E.,Williams, Shirley M.,Anthes, John C.,Rivelli, Maria A.,Corboz, Michel R.,Hey, John A.
scheme or table, p. 5004 - 5008 (2010/10/05)
A structure-activity relationship study of the lead piperazinylcarbonylpiperidine compound 3 resulted in the identification of 4-benzimidazolyl-piperidinylcarbonyl-piperidine 6h as a histamine-3 (H 3) receptor antagonist. Additional optimizatio
PIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 33-34, (2008/12/08)
The present invention relates to Compounds of Formula (I), compositions comprising the compounds, and methods of using the compounds to treat or prevent pain, diabetes, a diabetic complication, impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) in a patient.
1-(4-PIPERIDINYL) BENZIMIDAZOLONES AS HISTAMINE H3 ANTAGONISTS
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Page 18, (2010/02/04)
Disclosed are histamine H3 antagonists of the formula (I) wherein R1 is benzimidazolone derivative, M1 and M2 are optionally substituted carbon or nitrogen, R2 includes optionally substituted aryl or heteroaryl, and the remaining variables are as defined
Reductive amination of piperidines with aldehydes using borane-pyridine
Moormann
, p. 789 - 795 (2007/10/02)
Borane-pyridine complex (BAP) was found to be an excellent replacement for NaCNBH3 in the Borch reduction. Assorted aromatic, heterocyclic and aliphatic aldehydes were reacted with various substituted piperidines using standardized conditions.
