1380310-89-3Relevant academic research and scientific papers
Enantioselective Reductive Cross-Coupling of Aryl/Alkenyl Bromides with Benzylic Chlorides via Photoredox/Biimidazoline Nickel Dual Catalysis
Cheng, Xiaokai,Fang, Qun,Li, Tongtong,Lu, Jiamin,Lu, Zhan,Wang, Huifeng
supporting information, (2022/02/07)
The asymmetric reductive arylation and alkenylation of benzylic chloride under photoredox/nickel dual catalysis using chiral biimidazoline (BiIm) ligand is reported to access 1,1-diaryl alkanes and aryl allylic compounds with good yield as well as stereo-
Stereo- And Enantioselective Benzylic C-H Alkenylation via Photoredox/Nickel Dual Catalysis
Cheng, Xiaokai,Li, Tongtong,Liu, Yuting,Lu, Zhan
, p. 11059 - 11065 (2021/09/13)
A stereo- and enantioselective benzylic C-H alkenylation via photoredox/nickel catalysis is reported. Readily available alkylbenzenes and alkenyl bromides including complicated molecules undergo this cross-coupling reaction smoothly to afford chiral allylic compounds in up to 93% ee and >20/1E/Zratio under mild reaction conditions with good functional group tolerance. A triplet-energy-transfer-inhibiting strategy is developed for the stereoselective synthesis of alkenes under visible-light photocatalysis. The coordination pattern of nickel with chiral bis-imidazoline ligand has been illustrated based on nonlinear effect experiments and X-ray diffraction.
