1380328-49-3

Upstream product

• 1268519-07-8 (2R,3R)-1-(ethoxycarbonyl)-2,3-bis(3',5'-dibromophenyl)cyclopropane-1-carboxylic acid 
• 1380328-50-6 (2R,3R)-2,3-bis(3,5-dibromophenyl)cyclopropane-1,1-dicarboxylic acid 
• 1380328-51-7 (2R,3R)-2,3-bis(3,5-dibromophenyl)-N,N'-bis(2-hydroxyethyl)cyclopropane-1,1-dicarboxamide 
• 1380328-52-8 2,2'-[(2R,3R)-2,3-bis(3,5-dibromophenyl)cyclopropylidene]bis[4,5-dihydrooxazole] 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

Synthesis of a novel C2-symmetric bis-oxazoline (=bis[4,5-dihydrooxazole]) and its application as chiral ligand in asymmetric transition metal catalysis

The new C2-symmetric bis-oxazoline (=bis[4,5-dihydrooxazole]) 2 with a chiral trans-(2R,3R)-2,3-bis(3,5-diphenylphenyl)cyclopropylidene (=trans-(2R,3R)-2,3-bis([1,1′: 3′,1″-terphenyl]-5′-yl) cyclopropylidene) backbone was efficiently synthesized (Scheme). All synthetic steps were easy to perform and led to the desired product in good overall yields. Compound 2 was tested and compared as ligand in several enantioselective catalytic reactions such as palladium(0)-catalyzed enantioselective allylic alkylations and copper(I)-catalyzed enantioselective cyclopropanations and aziridinations. Copyright